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NORI has developed a highly targeted pro-oxidant nutraceutical that disables the two major antioxidant defense systems in cancer cells. SELQUINOX® is composed of a synergistic cocktail of natural compounds designed to selectively trigger cancer cell death.
SELQUINOX® is a patent-pending nutraceutical tablet formulation that is a redox-active pro-oxidant. The SEL in the name is for SELENIUM and the QUIN is for QUINONE, OX denotes OXIDATION. SELQUINOX® is a selenium and quinone based pro-oxidant that selectively increases ROS in cancer cells. SELQUINOX® is composed of sodium selenite, a natural quinone, vitamin B6 (P5P), iron, copper, zinc and manganese. All active ingredients are highly bioavailable.
SELQUINOX® is essentially the NORI protocol within a single tablet to simplify administration and lower cost. The NORI protocol is proving to be highly effective and the single tablet approach is proving to be equally effective. No more reaching for multiple bottles of supplements and nutraceuticals. SELQUINOX® is compatible with all conventional therapies.
The dosages of all of the active ingredients in SELQUINOX® are well below what would cause any adverse effects of toxicity. The combination of ingredients is highly synergistic allowing for very fafe dosages of all active ingredients. The tablet is formulated and manufactured for slow gradual release and is enteric coated to limit dissolution in the stomach. SELQUINOX® is typically taken for 4-5 consecutive days per week with a 2-3 day washout interval.
SELQUINOX® disables two key antioxidant systems, glutathione and thioredoxin. In addition, the quinone component both elevates oxidative stress and maintains redox recycling. Excessive oxidative stress triggers apoptosis and ferroptosis. Iron, copper, zinc and manganese are ferroptosis inducers.
SELQUINOX® contains vitamin B6 (P5P) and iron which non-enzymatically degrades the amino acid cysteine which is necessary for glutathione synthesis. A plant-based diet is helpful in limiting the intake of cysteine (cystine).
SELQUINOX® reduces the expression of immune checkpoints. Sodium selenite helps to enable natural killer cell activity against cancer cells. Vitamin B6 (P5P) lowers the expression of PD-L1 enabling CD8+ T cells to recognize cancer cells as abnormal.
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